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Click chemistry 點(diǎn)擊化學(xué) 鏈接化學(xué)

點(diǎn)擊化學(xué)工具:DBCO，TCO，四嗪，疊氮化物，炔烴和相關(guān)試劑。
DBCO Reagents
The dibenzocyclooctyne group (DBCO) allows Copper-free Click Chemistry to be done with live cells, whole organisms, and non-living samples.
DBCO-C6-NHS Ester  DBCO-C6-NHS Ester is an amine-reactive building block used for modification of amine-containing molecule in organic media.
DBCO-NHS Ester  DBCO-NHS Ester is an amine-reactive building block used for modification of amine-containing molecule in organic media.
DBCO-Sulfo-NHS Ester  DBCO-Sulfo-NHS Ester is water-soluble reagent that enables simple and efficient labeling of antibodies, proteins and any other primary amine-containing macromolecules with DBCO moiety in aqueous buffers.
DBCO-PEG4-NHS Ester  DBCO-PEG4-NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond.
DBCO-PEG5-NHS Ester  DBCO-PEG5-NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond.
DBCO-PEG13-NHS Ester  DBCO-PEG13-NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary azide-containing molecules.
PC DBCO-NHS Ester  Photocleavable DBCO-NHS ester reagent contains an amine reactive group linked to DBCO moiety through a spacer arm containing a photocleavable moiety.
DBCO-C6-Acid  DBCO-C6-Acid is an analog of DBCO-Acid with extended 6-carbon atom spacer arm.
DBCO-Acid  DBCO-Acid is an amine-reactive non-activated building block used for derivatizing amine-containing molecule in the presence of activators (e.g. EDC, or HATU) through a stable amide bond.
DBCO-PEG5-Acid  DBCO-PEG5-Acid is an amine-reactive, non-activated building block with enhanced solubility in aqueous media used for derivatizing amine-containing molecule in the presence of activators (e.g. EDC, or HATU) through a stable amide bond.
DBCO-Amine  DBCO-Amine is a simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond.
DBCO-PEG3-Amine  DBCO-PEG3-Amine is a carboxyl-reactive building block with enhanced solubility in aqueous media used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.
Sulfo DBCO-Amine  Sulfo DBCO-Amine is a water-soluble building block used to derivatize carboxyl-containing molecules or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond. The hydrophilic sulfonated spacer arm greatly improves water solubility of DBCO derivatized molecules, in many cases making it completely soluble in aqueous media.
Sulfo DBCO-PEG4-Amine  Sulfo DBCO-PEG4-Amine is a water-soluble reagent used to derivatize carboxyl-containing molecules or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond.
DBCO-Maleimide  DBCO-Maleimide enables simple and efficient incorporation of DBCO moiety onto cysteine-containing peptides or other thiol-containing molecules.
DBCO-PEG4-Maleimide  DBCO-PEG4-Maleimide enables simple and efficient incorporation of DBCO moiety onto antibodies, cysteine-containing peptides and other thiol-containing molecules.
Bis-sulfone-PEG4-DBCO  Bis-sulfone-PEG4-DBCO is a bis-alkylating labeling reagent that enables site-specific incorporation of DBCO moiety onto antibodies to form well-defined conjugates.
Thiolinker-DBCO  ThiolinkerTM-DCBO is a water-soluble bis-alkylating labeling reagent enables site-specific incorporation of DBCO moiety onto antibodies in well-defined fashion.
MB 488 DBCO  MB? 488 DBCO is a bright, green fluorescent probe with excitation ideally suited for the 488 nm laser line.
MB 543 DBCO  MB? 543 DBCO is an orange colored fluorescent probe with absorption and emission maxima at 544 and 560 nm, respectively.
MB 594 DBCO  MB? 594 is a bright, red fluorescent probe with absorption and emission maxima similar to Texas Red dye or Alexa Fluor 594®.
Carboxyrhodamine 110 DBCO  Carboxyrhodamine110 DBCO dye reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
TAMRA DBCO  TAMRA DBCO dye reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
Cy3 DBCO  Cy3 DBCO dye reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
Cy5 DBCO  Cy5 DBCO dye reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
Cy5.5 DBCO  Cy5.5 DBCO dye reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
Cy7 DBCO  Cy7 DBCO dye reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
DBCO-PEG4-Biotin  DBCO-PEG4-Biotin reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
WS DBCO-Biotin  A water-soluble, azide-reactive biotinylation reagent WS DBCO-Bitoin reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole.
DBCO-PEG4-Desthiobiotin  Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015M, respectively).
Dde Biotin-DBCO  Dde Biotin-DBCO is an azide-reactive biotin probe that allows for efficient release of the captured biomolecules from streptavidin.
PC DBCO-Biotin  PC Biotin-DBCO is an azide-reactive photoclevable biotin probe that allows for reagent-free release of the captured biomolecules from streptavidin.
WS-PC DBCO-Biotin  WS-PC Biotin-DBCO is water soluble, azide-reactive photoclevable biotin probe that allows for reagent-free release of the captured biomolecules from streptavidin.
Diazo Biotin-DBCO  Diazo Biotin-DBCO contains a biotin moiety linked to an DBCO group through a sodium dithionite (Na2S2O4) cleavable diazo linker.
DBCO-mPEG, 5 kDa  DBCO-activated PEGylation reagents react with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures
DBCO-mPEG, 10 kDa  DBCO-activated PEGylation reagents react with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
DBCO-mPEG, 20 kDa  DBCO-activated PEGylation reagents react with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
DBCO-mPEG, 30 kDa  DBCO-activated PEGylation reagents react with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
DBCO-PEG12-MMAE  DBCO-containing auristatin drug used to create antibody-drug conjugates via SPAAC reaction.
Methyltetrazine-DBCO  Heterobifunctional reagents used for converting azido-containing peptides or protein into tetrazine-modified peptides or protein without the need for catalyst or axillary reagents.
Methyltetrazine-PEG12-DBCO  Heterobifunctional reagents used for converting azido-containing peptides or protein into tetrazine-modified peptides or protein without the need for catalyst or axillary reagents.
DBCO-PEG4-DBCO  DBCO-PEG4-DBCO is a homobifunctional azide-to-azide cross-linker.
TCO-PEG12-DBCO  Heterobifunctional reagents are used for converting azido-containing biomolecules into TCO-modified biomolecules.
DBCO-PEG4-Hydroxyl  A modification reagent containing a long 4-unit polyethylene glycol (PEG4) spacer arm and a terminal primary hydroxyl group.
Tetrazine Reagents
Tetrazine-containing reagents are suitable for the introduction of a functional group (e.g. Amine or NHS Ester) to Cyclooctene-labeled molecules via Cu-free Click Chemistry an Tetrazine group to vario
Tetrazine-NHS Ester  An amine-reactive building block with exceptional kinetics.
Methyltetrazine-NHS Ester  An amine-reactive building block
Tetrazine-Sulfo-NHS Ester  A water-soluble reagent for labeling antibodies, proteins and other molecules containing primary amines.
Methyltetrazine-Sulfo-NHS Ester  A water-soluble amine-reactive labeling reagent
Tetrazine-PEG5-NHS Ester  An amine-reactive labeling reagents with enhanced reactivity and water solubility.
Methyltetrazine-PEG4-NHS Ester  An amine-reactive labeling reagents with enhanced stability and water solubility
Methyltetrazine-PEG5-NHS Ester  An amine-reactive labeling reagent with hydrophilic PEG5 spacer arm
Methyltetrazine-PEG4-Sulfo-NHS Ester  A water-soluble reagent for labeling antibodies, proteins and other molecules containing primary amines
Methyltetrazine-Acid  An amine-reactive, non-activated building block.
Tetrazine-Acid  An amine-reactive, non-activated building block with exceptional kinetics.
Methyltetrazine-PEG4-Acid  An amine-reactive, non-activated building block with enhanced stability and water solubility.
PC Methyltetrazine-NHS Ester  An amine-reactive, photocleavable labeling reagent.
Methyltetrazine-Amine  A carboxyl-reactive building block containing tetrazine moiety.
Tetrazine-Amine  A carboxyl-reactive building block with exceptional kinetics.
Methyltetrazine-Propylamine  A carboxyl-reactive building block with enhanced stability.
Methyltetrazine-PEG4-Amine  A carboxyl-reactive building block with enhanced stability and water solubility.
Methyltetrazine-PEG4-Maleimide  A mid-length, sulfhydryl-reactive labeling reagent with enhanced water-solubility provided by a PEG4 spacer.
Bis-sulfone-PEG4-Tetrazine  A bis-alkylating reagent used to introduce tetrazine moiety onto antibody in well-defined fashion.
Thiolinker-Tetrazine  A water-soluble, thiol-reactive, bis-alkylating labeling reagent.
Methyltetrazine-DBCO  A water-soluble azide-to-TCO heterobifunctional crosslinker
Methyltetrazine-PEG12-DBCO  An azide-to-TCO heterobifunctional crosslinker with a hydrophilic PEG12 spacer arm
Methyltetrazine-PEG4-Alkyne  Heterobifunctional reagent activated with terminal alkyne group and methyltetrazine moiety.
Methyltetrazine-PEG4-Azide  An alkyne-to-TCO heterobifunctional crosslinker with a hydrophilic PEG4 spacer arm.
Methyltetrazine-mPEG, 5 kDa  5 kDa, methyltetrazine-activated PEGylation reagent.
Methyltetrazine-mPEG, 10 kDa  10 kDa, methyltetrazine-activated PEGylation reagent.
Methyltetrazine-mPEG, 20 kDa  20 kDa, Methyltetrazine-activated PEGylation reagent.
Methyltetrazine-mPEG, 30 kDa  30 kDa, Methyltetrazine-activated PEGylation reagent.
Biotin-PEG4-Methyltetrazine  A methyltetrazine-activated biotinylation reagent with a hydrophilic PEG4 spacer arm.
Cy3 Tetrazine  A tetrazine-activated Cy5 dye.
Cy3 Methyltetrazine  A methyltetrazine-activated Cy3 dye for chemoselective labeling and detection of TCO-tagged molecules.
TAMRA Tetrazine  An orange-to-red fluorescence-emitting, tetrazine-activated probe.
TAMRA Methyltetrazine  An orange-to-red fluorescence-emitting, methyltetrazine-activated probe.
Cy5 Tetrazine  A tetrazine-activated Cy5 dye.
Cy5 Methyltetrazine  A methyltetrazine-activated Cy5 dye for chemoselective labeling and detection of TCO-tagged molecules.
Cy7 Methyltetrazine  A water-soluble, tetrazine-activated NIR probe.
Tetrazine-PEG4-NOTA
MPEG-Tetrazine甲氧基聚乙二醇-四嗪磺基  MPEG-Tetrazine甲氧基聚乙二醇-四嗪磺基是YARE-PEG旗下高質(zhì)量產(chǎn)品
Azide Reagents
Azido-containing building blocks, labeling reagents, haptens, and fluorescent probes
PC Biotin-Azide  An azide-activated photoclevable biotin probe.
PC Azido-NHS Ester  An amine-reactive, photocleavable labeling reagent.
Azido-Propylamine  A carboxyl-reactive building block.
Alkyne Reagents
Alkyne-based labeling reagents, fluorescent probes and haptens for Cu-catalyzed click chemistry
Propargyl-NHS Ester  An amine-reactive building block.
PC Alkyne-NHS Ester  An amine-reactive, photocleavable labeling reagent.
Propargyl-Maleimide  A maleimide-activated, building block.
PC Biotin-Alkyne  An azide-activated photoclevable biotin probe
Dde Biotin-Alkyne  An azide-reactive, hydrazine-cleavable biotin probe.
Diol Biotin-Alkyne  An azide-reactive, sodium periodate cleavable biotin probe.
Diazo Biotin-Alkyne  An azide-reactive, sodium dithionite cleavable biotinylation reagent.
Alkyne -PEG-Alkyne炔烴-聚乙二醇-炔烴  Alkyne -PEG-Alkyne炔烴-聚乙二醇-炔烴是YARE-PEG旗下高質(zhì)量產(chǎn)品
TCO Reagents
Trans-Cyclooctene (TCO)-based labeling reagents, building blocks, and crosslinkers
TCO-NHS Ester  An amine-reactive, succinimidyl carbonate/NHS functionalized cyclooctene building block
TCO-PNB Ester  An amine-reactive, cyclooctene-containing building block.
TCO-PEG4-NHS Ester  An amine-reactive labeling reagents with enhanced solubility in aqueous buffers
TCO-PEG12-NHS Ester  Amine-reactive labeling reagents with extended PEG12 spacer arm
TCO-PEG4-Acid  Amine-reactive, non-activated building block with enhanced solubility in aqueous buffers
TCO-PEG3-Maleimide  A sulfhydryl-reactive labeling reagent with hydrophilic PEG4 spacer arm.
Cy5-TCO  A TCO-activated Cy5 dye.
TCO-Amine HCl Salt  A carboxyl-reactive building block.
TCO-PEG3-Amine  A carbonyl-reactive building block with enhanced solubility in aqueous media.
TCO-PEG12-DBCO  An azide-to-tetrazine heterobifunctional cross-linker with a hydrophilic PEG12 spacer arm
MPEG-TCO  Methoxypolyethylene glycol-Total Cost of Ownership MPEG-TCO

Click chemistry 點(diǎn)擊化學(xué) 鏈接化學(xué)

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Click chemistry 點(diǎn)擊化學(xué) 鏈接化學(xué)

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