我公司致力于為客戶(hù)提供高純度、低成本的活性重組蛋白，包括重組人TIMP-1在內(nèi)的各類(lèi)受體、細(xì)胞因子、生長(zhǎng)因子、轉(zhuǎn)錄因子、激素、酶、毒性蛋白、病毒抗原等。

北京百奧萊博科技有限公司是一家專(zhuān)業(yè)的生物試劑銷(xiāo)售公司。公司主要經(jīng)營(yíng)血清、抗原、抗體等生物試劑產(chǎn)品，可以為您提供專(zhuān)業(yè)的技術(shù)服務(wù)，以?xún)?yōu)良的價(jià)格、優(yōu)質(zhì)的服務(wù)、優(yōu)先的理念，滿(mǎn)足客戶(hù)的各方面的需求，與國(guó)內(nèi)多家企業(yè)、單位建立了良好的長(zhǎng)期合作關(guān)系，擁有較好的企業(yè)信譽(yù)和品牌形象。 主營(yíng)產(chǎn)品:血清、抗體、抗原、核酸提取、核酸純化等生化試劑

特別提示：包括重組人TIMP-1(金屬蛋白酶1組織抑制劑)在內(nèi)，本公司的所有產(chǎn)品僅可用于科研實(shí)驗(yàn)，嚴(yán)禁用于臨床醫(yī)療及其他非科研用途！

產(chǎn)品名稱(chēng)：重組人TIMP-1(金屬蛋白酶1組織抑制劑)
英文名稱(chēng)：Recombinant Human Tissue Inhibitor of metalloproteinases 1
產(chǎn)品貨號(hào)：JN1692
產(chǎn)品規(guī)格：10μg|50μg|500μg|1mg

本品由我們的哺乳動(dòng)物細(xì)胞表達(dá)系統(tǒng)制備而成，目的基因編碼的Cys24-Ala207在C端含有His標(biāo)簽。

TIMP-1質(zhì)量控制：＞95%(還原性SDS-PAGE)

TIMP-1制劑：凍干品

TIMP-1保存：
凍干蛋白置于-20℃以下可長(zhǎng)期保存，室溫條件下可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4～7℃保存2～7天，可分裝后置于-20℃保存三個(gè)月。

TIMP-1復(fù)溶：
打開(kāi)試劑管前請(qǐng)先離心。
復(fù)溶濃度推薦大于100 μg/ml。
凍干蛋白請(qǐng)溶于ddH2O。
復(fù)溶后，請(qǐng)根據(jù)用量分裝凍存，避免反復(fù)凍融。

關(guān)于TIMP-1：
Tissue Inhibitor of metalloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix metalloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. Timp-1 complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. It also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16, without MMP-14.

根據(jù)您的關(guān)注的重組人TIMP-1(金屬蛋白酶1組織抑制劑)，重組人金屬蛋白酶1組織抑制劑，重組金屬蛋白酶1組織抑制劑，重組人Tissue Inhibitor of metalloproteinases 1，rTIMP-1，重組TIMP-1，金屬蛋白酶1組織抑制劑，重組Tissue Inhibitor of metalloproteinases 1，重組人TIMP-1(金屬蛋白酶1組織抑制劑)，rhTIMP-1，Recombinant Human Tissue Inhibitor of metalloproteinases 1，重組人TIMP-1，JN1692，百奧萊博，，，您可能還對(duì)以下產(chǎn)品有需求：



名稱(chēng)：重組小鼠RANK(TNFRSF11A)(CD265)
貨號(hào)：JN0509
規(guī)格：10μg|50μg|500μg|1mg
本品由我們的哺乳動(dòng)物細(xì)胞表達(dá)系統(tǒng)制備而成，目的基因編碼的Val31-Ser214在C端含有His標(biāo)簽。

RANK/TNFRSF11A/CD265質(zhì)量控制：＞95%(還原性SDS-PAGE)

RANK/TNFRSF11A/CD265制劑：凍干品

RANK/TNFRSF11A/CD265保存：
凍干蛋白置于-20℃以下可長(zhǎng)期保存，室溫條件下可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4～7℃保存2～7天，可分裝后置于-20℃保存三個(gè)月。

RANK/TNFRSF11A/CD265復(fù)溶：
打開(kāi)試劑管前請(qǐng)先離心。
復(fù)溶濃度推薦大于100 μg/ml。
凍干蛋白請(qǐng)溶于ddH2O。
復(fù)溶后，請(qǐng)根據(jù)用量分裝凍存，避免反復(fù)凍融。

關(guān)于RANK/TNFRSF11A/CD265：
Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member oftumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide, 184 aa extracellular region , a 20 aa transmembrane domain and a 391 aa cytoplasmic region. Human and murine RANK share 81% aa identity in their extracellular domains. RANK is ubiquitous highly expressed in trabecular bone, thymus, small intestine, lung, brain and kidney, but weakly expressed in spleen and bone marrow. After binding its ligand RANKL, RANK can activate signaling pathways such as NF-κB, JNK, ERK, p38, and Akt/PKB, through TRAF protein phosphorylation. RANK/TNFRSF11A signaling is largely considered to be growth promoting and apoptosis reducing such as the effects observed in osteoclasts. RANK/TNFRSF11A was also found to be involved in the regulation of interactions between T-cells and dendritic cells.

關(guān)注重組人TIMP-1(金屬蛋白酶1組織抑制劑)，重組人金屬蛋白酶1組織抑制劑，重組金屬蛋白酶1組織抑制劑，重組人Tissue Inhibitor of metalloproteinases 1，rTIMP-1，重組TIMP-1，金屬蛋白酶1組織抑制劑，重組Tissue Inhibitor of metalloproteinases 1，重組人TIMP-1(金屬蛋白酶1組織抑制劑)，rhTIMP-1，Recombinant Human Tissue Inhibitor of metalloproteinases 1，重組人TIMP-1，JN1692，百奧萊博，，的同時(shí)，為您推薦更多您可能感興趣的產(chǎn)品：


JN0381 重組人白介素IL-7(白細(xì)胞介素7) 10μg|50μg|500μg|1mg
JN0389 重組小鼠白介素IL-36α(白細(xì)胞介素36α) 10μg|50μg|500μg|1mg
JN0443 重組人TNFRSF5(CD40) 10μg|50μg|500μg|1mg
JN1909 重組人Bcl-2相關(guān)蛋白A1(BCL2A1) 10μg|50μg|500μg|1mg
JN1973 重組人Grancalcin蛋白 10μg|50μg|500μg|1mg
JN0559 重組人ASAM 10μg|50μg|500μg|1mg
JN0631 重組人髓鞘少突膠質(zhì)細(xì)胞糖蛋白(MOG) 10μg|50μg|500μg|1mg

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