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2070 ENPP1 Antibody (Human Specific) #2070

會員指數(shù): 企業(yè)認(rèn)證:

價(jià)格:電議

所在地:上海

型號:2070

更新時(shí)間:2013-07-27

瀏覽次數(shù):723

公司地址:

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產(chǎn)品簡介

"上海博耀生物銷售ENPP1 Antibody (Human Specific) #2070,CST原裝品質(zhì),價(jià)格優(yōu)惠,訂購ENPP1 Antibody (Human Specific) #2070

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"上海博耀生物銷售ENPP1 Antibody (Human Specific) #2070,CST原裝品質(zhì),價(jià)格優(yōu)惠,訂購ENPP1 Antibody (Human Specific) #2070,詳情請咨詢銷售人員!
產(chǎn)品詳細(xì)參數(shù)如下>>>>

產(chǎn)品名稱:ENPP1 Antibody (Human Specific) #2070
貨號:2070
品牌:CST(cell signaling)
抗體來源:Rabbit
克隆類型: Polyclonal
規(guī)格:
No. Size Price
2070S 100 ul (10 western blots) 詢價(jià)

抗體應(yīng)用:
Applications Reactivity Sensitivity MW (kDa) Source
W H Endogenous 140 Rabbit
Applications Key:  W=Western Blotting
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度: ENPP1 Antibody (Human Specific) detects endogenous levels of total ENPP1 protein.
來源及純化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln815 of human ENPP1. Antibodies were purified by protein A and peptide affinity chromatography.
抗體背景:

Ectonucleotide pyrophosphatase-phosphodiesterase 1 (ENPP1) is a single-pass, type II transmembrane protein primarily involved in ATP hydrolysis at the plasma membrane. Targeting of ENPP1 to the basolateral cell surface relies on the presence of a carboxy-terminal di-leucine-based signal (1). ENPP1 plays important roles in bone mineralization and soft tissue calcification (2-5). Mutations in the corresponding ENPP1 gene cause generalized arterial calcification in infancy (GACI) and idiopathic infantile arterial calcification (IIAC) (6,7). ENPP1 inhibits insulin receptor function and overexpression of this enzyme causes insulin resistance and glucose intolerance in mice (8,9). Genetic variants of ENPP1 have been associated with obesity and type 2 diabetes (10-12).

關(guān)鍵詞:CST,抗體,一抗{byao_back}{byao_back2}

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