"上海博耀生物銷售eIF4E (C46H6) Rabbit mAb #2067，CST原裝品質(zhì)，價(jià)格優(yōu)惠，訂購(gòu)eIF4E (C46H6) Rabbit mAb #2067，詳情請(qǐng)咨詢銷

"上海博耀生物銷售eIF4E (C46H6) Rabbit mAb #2067，CST原裝品質(zhì)，價(jià)格優(yōu)惠，訂購(gòu)eIF4E (C46H6) Rabbit mAb #2067，詳情請(qǐng)咨詢銷售人員！
產(chǎn)品詳細(xì)參數(shù)如下>>>>

產(chǎn)品名稱：eIF4E (C46H6) Rabbit mAb #2067
貨號(hào)：2067
品牌：CST(cell signaling)
抗體來(lái)源：Rabbit
克隆類型： Monoclonal
規(guī)格：

No.	Size	Price
2067P	40 ul (4 western blots)	詢價(jià)
2067S	100 ul (10 western blots)	詢價(jià)

抗體應(yīng)用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IHC-P	H M R Mk	Endogenous	25	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度： eIF4E (C46H6) Rabbit mAb detects endogenous levels of total eIF4E protein.
來(lái)源及純化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to human eIF4E protein.
抗體背景：

Eukaryotic initiation factor 4E (eIF4E) binds to the mRNA cap structure to mediate the initiation of translation (1,2). eIF4E interacts with eIF4G, a scaffold protein that promotes assembly of eIF4E and eIF4A into the eIF4F complex (2). eIF4B is thought to assist the eIF4F complex in translation initiation. Upon activation by mitogenic and/or stress stimuli mediated by Erk and p38 MAPK, Mnk1 phosphorylates eIF4E at Ser209 in vivo (3,4). Two Erk and p38 MAPK phosphorylation sites in mouse Mnk1 (Thr197 and Thr202) are essential for Mnk1 kinase activity (3). The carboxy-terminal region of eIF4G also contains serum-stimulated phosphorylation sites, including Ser1108, Ser1148, and Ser1192 (5). Phosphorylation at these sites is blocked by the PI3 kinase inhibitor LY294002 and by the FRAP/mTOR inhibitor rapamycin.

關(guān)鍵詞：CST，抗體，一抗{byao_back}{byao_back2}

相關(guān)產(chǎn)品：
ab103108/Anti-GALNTL5 antibody
ab103133/Anti-GBE1 antibody
ab102688/Anti-CCDC67 antibody
Anti-MOG髓鞘少樹(shù)突膠質(zhì)細(xì)胞糖蛋白抗體
Anti-BACE1/ASP2β分泌酶抗體
Anti-PCDHGC4原鈣粘蛋白γC4抗體
Anti-NKA/Neurokinin A神經(jīng)激肽A抗體
ab103697/Anti-EPC2 antibody
Anti-Adiponectin receptor 2脂聯(lián)素受體2抗體
Anti-LHR/LHCGR促黃體生成素受體抗體
ab103608/Anti-CCDC21 antibody
Anti-β-Amyloid 1-42(CT)β淀粉樣肽1-42 (C端)抗體
Anti-HSL/LIPE荷爾蒙敏感脂肪酶抗體
Anti-Insulin Receptor/CD220胰島素受體抗體
ab104299/Anti-CENPN antibody
ab103529/Anti-eIF4G1 antibody"
本頁(yè)產(chǎn)品地址：http://m.lgsztm.com/sell/show-3242142.html