產品簡介
"上海博耀生物銷售PKD/PKCμ Antibody #2052,CST原裝品質,價格優惠,訂購PKD/PKCμ Antibody #2052,詳情請咨詢銷售人員!產品
產品說明
"上海博耀生物銷售
PKD/PKCμ Antibody #2052,CST原裝品質,價格優惠,訂購
PKD/PKCμ Antibody #2052,詳情請咨詢銷售人員!
產品詳細參數如下>>>>
產品名稱:PKD/PKCμ Antibody #2052
貨號:2052
品牌:CST(cell signaling)
抗體來源:Rabbit
克隆類型:
Polyclonal
規格:
| No. |
Size |
Price |
| 2052P |
40 ul (4 western blots) |
詢價 |
| 2052S |
100 ul (10 western blots) |
詢價 |
抗體應用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W F |
H M R Mk |
Endogenous |
115 |
Rabbit |
Applications Key:
W=Western Blotting
F=Flow Cytometry
Reactivity Key:
H=Human
M=Mouse
R=Rat
Mk=Mon
key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度:
PKD/PKCmu Antibody detects endogenous levels of total PKD1/PKCmu protein. This antibody may also react with isoform PKD2, in some species.
來源及純化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser916 of mouse PKD. Antibodies are purified by protein A and peptide affinity chromatography.
抗體背景:
Activation of PKC is one of the earliest events in a cascade leading to a variety of cellular responses such as secretion, gene expression, proliferation and muscle contraction (1,2). Protein kinase D (PKD), also called PKCμ, is a serine/threonine kinase whose activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway (3-5). In addition to the two activation loop sites, the carboxy-terminal Ser916 has been identified as an autophosphorylation site for PKD/PKCμ. Phosphorylation at Ser916 correlates with PKD/PKCμ catalytic activity (6).
關鍵詞:CST,抗體,一抗{byao_back}{byao_back2}
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