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2052 PKD/PKCμ Antibody #2052

會員指數: 企業認證:

價格:電議

所在地:上海

型號:2052

更新時間:2013-07-27

瀏覽次數:849

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"上海博耀生物銷售PKD/PKCμ Antibody #2052,CST原裝品質,價格優惠,訂購PKD/PKCμ Antibody #2052,詳情請咨詢銷售人員!產品

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"上海博耀生物銷售PKD/PKCμ Antibody #2052,CST原裝品質,價格優惠,訂購PKD/PKCμ Antibody #2052,詳情請咨詢銷售人員!
產品詳細參數如下>>>>

產品名稱:PKD/PKCμ Antibody #2052
貨號:2052
品牌:CST(cell signaling)
抗體來源:Rabbit
克隆類型: Polyclonal
規格:
No. Size Price
2052P 40 ul (4 western blots) 詢價
2052S 100 ul (10 western blots) 詢價

抗體應用:
Applications Reactivity Sensitivity MW (kDa) Source
W F H M R Mk Endogenous 115 Rabbit
Applications Key:  W=Western Blotting  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度: PKD/PKCmu Antibody detects endogenous levels of total PKD1/PKCmu protein. This antibody may also react with isoform PKD2, in some species.
來源及純化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser916 of mouse PKD. Antibodies are purified by protein A and peptide affinity chromatography.
抗體背景:

Activation of PKC is one of the earliest events in a cascade leading to a variety of cellular responses such as secretion, gene expression, proliferation and muscle contraction (1,2). Protein kinase D (PKD), also called PKCμ, is a serine/threonine kinase whose activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway (3-5). In addition to the two activation loop sites, the carboxy-terminal Ser916 has been identified as an autophosphorylation site for PKD/PKCμ. Phosphorylation at Ser916 correlates with PKD/PKCμ catalytic activity (6).

關鍵詞:CST,抗體,一抗{byao_back}{byao_back2}

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