"上海博耀生物銷售MSH2 (D24B5) Rabbit mAb #2017，CST原裝品質，價格優惠，訂購MSH2 (D24B5) Rabbit mAb #2017，詳情請咨詢銷售

"上海博耀生物銷售MSH2 (D24B5) Rabbit mAb #2017，CST原裝品質，價格優惠，訂購MSH2 (D24B5) Rabbit mAb #2017，詳情請咨詢銷售人員！
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產品名稱：MSH2 (D24B5) Rabbit mAb #2017
貨號：2017
品牌：CST(cell signaling)
抗體來源：Rabbit
克隆類型： Monoclonal
規格：

No.	Size	Price
2017P	40 ul (4 western blots)	詢價
2017S	100 ul (10 western blots)	詢價

抗體應用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IHC-P IF-IC F	H M	Endogenous	100	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)  IF-IC=Immunofluorescence (Immunocytochemistry)  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度： MSH2 (D24B5) XP^® Rabbit mAb detects endogenous levels of total MSH2 protein.
來源及純化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues at the amino terminus of human MSH2.
抗體背景：

The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between non-identical DNA sequences and induces both checkpoint and apoptotic responses following certain types of DNA damage (1). MSH2 (MutS homologue 2) forms the hMutS-α dimer with MSH6 and is an essential component of the mismatch repair process. hMutS-α is part of the BRCA1-associated surveillance complex (BASC), a complex that also contains BRCA1, MLH1, ATM, BLM, PMS2 proteins and the Rad50-Mre11-NBS1 complex (2).Mutations in MSH2 have been found in a large proportion of hereditary non-polyposis colorectal cancer (Lynch Syndrome), the most common form of inherited colorectal cancer in the Western world (3). Mutations have also been associated with other sporadic tumors.

關鍵詞：CST，抗體，一抗{byao_back}{byao_back2}

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